Infection Control Needs

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An overwhelming need to arrest the hospital-acquired super-bug infection rates in the U.S. and World by the Health Care Industry

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Recent analysis from Frost & Sullivan found that the U.S. antimicrobial coatings markets earned revenues of $175.4M in 2005 with estimates to reach $558.7M by 2012

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Healthcare related infections (HRIs), An Emerging Global Crisis

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70% of HRIs are due to highly antibiotic resistant organisms

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$4.5 billion in additional costs

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8 million excess hospital days

ICET has identified a clear need to develop biopolymeric interfacial surface which:
    * Prevent adherence and survival of bacteria and yeast
    * Prevent Calcium and Magnesium Salt Deposits on the Material
 
Extruded Products with Active Formula

ICET can provide its custom antimicrobial formulations for compounding with certain medical resins for dry extrusion processes. The ICET active formula could be compounded with medical or consumer grade resins and extruded to a desired shape. The temperature limitations for this process are 300 F.

Currently an extruded antimicrobial catheter accessory device is being readied for clinical trial.

ICET Links:

Antimicrobial Catheter Accessory Device

 
Surface Coating

ICET has addressed these and developed highly lubricious and efficacious surface coating formulations with antimicrobial properties. Such formulations are coatable on silicone, polyurethane, PVC, and latex devices.

The coating process is simple such as dip coating and a few milligrams of the coating could provide active protection. Ready to coat or custom formulations can be provded.

Ready-coat formulations for medical grade silicone tubing or devices are also available. Such coatings applied on Foley catheters have been found to be biocompatible and these materials are in the process of being clinical evaluated. The application of ICET formulations to a medical device requires FDA approval. ICET is willing to provide supporting data during the application process under a suitable agreement.

Coating services on a lab scale, pilot scale and manufacturing will be provided under a suitable contract. Our business process is (1) Assessment of client's needs, (2) Feasibility study on a cost share basis with rthe customer, (3) Customization: the chemical formula, process, and concentrations are optimized to meet the product performance, (4) An application specific license agreement or a mutually acceptable alternative business agreement. Alternatively ICET could be the exclusive supplier of the antimicrobials for the specific application, (5) Pilot manufacture and technical support.

ICET Links:

Long-term sustained release antimicrobial and anti-adhesive foley catheters

Antimicrobial Technology for Food and Beverage Packaging